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CDH2 — RHOA
Pathways - manually collected, often from reviews:
Text-mined interactions from Literome
Laplante et al., J Neurobiol 2004
:
RhoA/ROCK and Cdc42
regulate cell-cell contact and
N-cadherin protein level during neurodetermination of P19 embryonal stem cells
Matsuda et al., J Mol Cell Cardiol 2006
:
RhoA and Rac1 activation was inhibited by the transfection of dominant negative N-cadherin, indicating that
RhoA and Rac1 were
activated by
N-cadherin in the oriented cardiac myocytes
Ordóñez-Morán et al., J Cell Biol 2008
(Colonic Neoplasms) :
As shown by the use of chemical inhibitors, dominant negative mutants and small interfering RNA,
RhoA-ROCK , and p38MAPK-MSK1 activation is
necessary for the induction of
CDH1/E-cadherin , CYP24, and other genes and of an adhesive phenotype by 1,25 ( OH ) ( 2 ) D ( 3 )
Taulet et al., J Biol Chem 2009
:
LR disruption inhibits myogenesis induction and
N-cadherin dependent
RhoA activation as does the perturbation of the N-cadherin-p120 catenin complex after p120 catenin knockdown ... Finally, we observe an
N-cadherin dependent accumulation of
RhoA at phosphatidylinositol 4,5-bisphosphate enriched cell contacts which is lost after LR disruption
Espejo et al., Am J Physiol Cell Physiol 2010
(Colonic Neoplasms) :
Adherens junction assembly is impaired following calcium switch in KM12C cells with stably knocked down PTP-PEST and is accompanied by an increase in the activity of Rac1 and a suppression of
RhoA activity in
response to
cadherin engagement