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HES2 — IL6
Text-mined interactions from Literome
Lv et al., Acta Anaesthesiol Scand 2005
:
HES significantly
reduced the increased hepatic levels of TNF-alpha, IL-1beta,
IL-6 , IL-8 and the mRNAs in the endotoxemic rats
Lv et al., J Int Med Res 2005
(Endotoxemia...) :
HES significantly
reduced the LPS induced increase in intestinal levels of TNF-alpha, IL-1beta,
IL-6 , IL-8 and their corresponding mRNAs
Lv et al., Anesth Analg 2006
(Endotoxemia) :
HES significantly
reduced the increased intestinal levels of tumor necrosis factor-alpha,
IL-6 , cytokine induced neutrophil chemoattractant-1, and the mRNAs in the endotoxemic rats
Wang et al., Int Immunopharmacol 2009
(Disease Models, Animal...) :
In addition, both
HES and BL could
attenuate the increase in TNF-alpha,
IL-6 , MPO levels and NF-kappaB activation
Feng et al., Int Immunopharmacol 2010
(Disease Models, Animal...) :
Meanwhile,
HES could significantly
reduce TNF-alpha,
IL-6 , and ICAM-1 mRNA, inhibit NF-kappaB activation, and down-regulate TLR2 and TLR4 expression in the brain
Grainger et al., J Exp Med 2010
(Chronic Disease...) :
HES induced IL-17 in the
presence of
IL-6 but did not promote Th1 or Th2 development under any conditions
Schick et al., BMC gastroenterology 2012
(Blood Coagulation Disorders...) :
HES improved liver microcirculation, cardiac index and DO2-I, but significantly
increased IL-1ß,
IL-6 and TNF-a levels and resulted in a mortality rate of 33 %