Gene interactions and pathways from curated databases and text-mining

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SREBF1 — SYTL4

Text-mined interactions from Literome

Kato et al., Cell Metab 2006 (Diabetes Mellitus, Experimental) : Granuphilin is activated by SREBP-1c and involved in impaired insulin secretion in diabetic mice
Oberkofler et al., J Mol Med (Berl) 2009 (Insulinoma) : Furthermore PGC-1beta, SREBP-1c , and FOXA2 overexpression augmented granuphilin promoter activity, whereas siRNA mediated gene knockdown of PGC-1beta reduced the effects of SREBP-1c and FOXA2 on granuphilin gene transcription and significantly increased glucose stimulated insulin release from INS-1E cells