Onisto et al., Int J Oncol 2005
(Neoplasm Invasiveness...) :
Exogenous expression of the ARMS specific PAX3-FKHR chimeric protein in RD cells increased MMP-2 activity and invasiveness ... Overall, our data suggest that a high level of MMP-2 protein and VEGF/VEGFR expression may contribute to the metastatic phenotype of ARMS cells and that exogenously induced PAX3-FKHR expression increases MMP-2 secretion and invasive capability of RMS cells
Tanaka et al., J Investig Dermatol Symp Proc 2009
:
Furthermore, FOXO1a-peptide induced opposite changes in COLIAI, MMP-1 , and MMP-2 expression