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INS — RPS6KA3

Pathways - manually collected, often from reviews:

• KEGG mTOR signaling pathway: IGF1/INS → RPS6KA1/RPS6KA2/RPS6KA3/RPS6KA6 (protein-protein, indirect effect)
  

Text-mined interactions from Literome

Osman et al., J Appl Physiol 2001 (Insulin Resistance...) : Seven weeks of training significantly increased basal and insulin stimulated ERK2 and RSK2 activities, as well as insulin stimulation of MAPK kinase activity
Markuns et al., Endocrinology 1999 (Diabetes Mellitus, Experimental) : In all three groups of rats, insulin significantly increased ERK2, RSK2 , Akt, and p70S6k activities ... RSK2 expression and insulin stimulated RSK2 activity were significantly elevated in diabetic rats compared with those in the control animals