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IFNG — RB1
Pathways - manually collected, often from reviews:
Text-mined interactions from Literome
Zhu et al., Oncogene 1999
:
pRB is
required for
interferon-gamma-induction of the MHC class II abeta gene ...
pRB is
required for
IFN-gamma-induction of MHC class II in human tumor cell lines, providing a potential link between tumor suppressors and the immune system
Musikacharoen et al., Blood 2005
:
Promoter analyses in a mouse macrophage cell line, RAW264.7, revealed that the 2508-bp region upstream of the transcriptional start site is sufficient for the full transcriptional
activation of the
IL12RB1 gene by
IFN-gamma or IL-15 ... Consistently, IL-15, as a histone deacetylase inhibitor, synergistically enhanced
IL12RB1 gene expression and promoter
activation by
IFN-gamma through increased protein binding to ETS/PU.1 and IRE/ISRE sites ... Additionally,
IL12RB1 promoter
activation by
IFN-gamma was enhanced by the coexpression of a coactivator protein, CBP