Gene interactions and pathways from curated databases and text-mining

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CA2 — DIO1

Text-mined interactions from Literome

Kamouchi et al., J Physiol 1999 : 5. Thapsigargin and 2,5-di-tert-butyl-1 , 4-benzohydroquinone ( BHQ ), inhibitors of the organellar Ca2+-ATPase , failed to activate IhTRP3
Togna et al., Toxicol Lett 2001 : Furthermore, cocaine significantly increased endothelium dependent relaxation response to 2,5-di-tert-butylhydroquinone , a sarcoplasmic Ca2+-ATPase pump inhibitor , in the aortic rings
Schilling et al., Biochem J 1992 (Ion Channel Gating) : To test this hypothesis in vascular endothelial cells, the effect of the Ca ( 2+ ) -ATPase/pump inhibitor 2,5-di-t-butylhydroquinone ( BHQ ) on cytosolic free Ca2+ concentration ([Ca2+]i) was examined
Wictome et al., FEBS Lett 1992 : 2,5-Di ( tert-butyl ) -1,4-benzohydroquinone has been shown to inhibit the Ca2+ , M ( 2+ ) -ATPase of sarcoplasmic reticulum with an affinity of 0.4 microM
Picard et al., J Biol Chem 2006 : In addition, we specifically demonstrate that in this E2P-like form of ATPase, the presence of thapsigargin, 2,5-di-tert-butyl-1,4-dihydroxybenzene , or cyclopiazonic acid prevents 45Ca2+ binding ( i.e. presumably prevents opening of the 45Ca2+ binding sites on the SR luminal side )
Pernollet et al., Biochem Biophys Res Commun 1996 : The effects of NO were compared to those of thapsigargin and 2,5-di- ( t-butyl ) -1,4-benzohydroquinone, two specific inhibitors of the sarco/endoplasmic reticulum Ca2+-ATPases
Jan et al., Eur J Pharmacol 1999 : Mechanism of rise and decay of 2,5-di-tert-butylhydroquinone induced Ca2+ signals in Madin Darby canine kidney cells ... We examined the effect of 2,5-di-tert-butylhydroquinone ( BHQ ) on intracellular Ca2+ concentrations ([Ca2+]i) measured by fura-2 fluorimetry in Madin Darby canine kidney ( MDCK ) cells