Gene interactions and pathways from curated databases and text-mining

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CA2 — PRM2

Text-mined interactions from Literome

Yamakage et al., Anesth Analg 1999 : Protamine and heparin-protamine complex dose-dependently inhibited both carbachol induced contraction of the muscle and increase in [ Ca2+ ] i
Elferink et al., Cell Biochem Funct 1992 : In the absence of Ca2+ , and in the presence of protamine , La3+ has an activating effect on exocytosis
Diaz-Sylvester et al., PloS one 2009 (Ion Channel Gating) : It has been reported that protamine ( > 10 microg/ml ) blocks single skeletal RyR1 channels and inhibits RyR1 mediated Ca2+ release from sarcoplasmic reticulum microsomes
Kimura et al., Biochim Biophys Acta 1987 : Protein kinase C phosphorylation of protamine is Ca2+ independent, but the addition of DNA renders it Ca2+ dependent
Gandini et al., FEBS Lett 1993 : IN is ineffective on PKC dependent protamine phosphorylation of protamine and on Ca2+ and phospholipid independent activity generated by mild hydrolysis with trypsin of PKC
Igarashi et al., Nat Toxins 1998 (Hemolysis) : The hemolytic activity of PRM2 was not affected by Ca2+ but was markedly affected by blood cell origin