Gene interactions and pathways from curated databases and text-mining

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MTA3 — TNF

Text-mined interactions from Literome

Moreno et al., Ann Neurol 2006 (Disease Models, Animal...) : Indeed, MTA suppressed the production of proinflammatory genes and cytokines ( interferon-gamma, tumor necrosis factor-alpha , and inducible nitric oxide synthase ) and increased the production of antiinflammatory cytokines ( interleukin-10 )
Ara et al., Hepatology 2008 : We previously showed that S-adenosylmethionine ( SAMe ) and its metabolite methylthioadenosine ( MTA ) blocked lipopolysaccharide (LPS) induced tumor necrosis factor alpha (TNFalpha) expression in RAW ( murine macrophage cell line ) and Kupffer cells at the transcriptional level without affecting nuclear factor kappa B nuclear binding
Li et al., Carcinogenesis 2012 (Cell Transformation, Neoplastic...) : S-adenosylmethionine ( SAMe ) and its metabolite methylthioadenosine ( MTA ) can inhibit lipopolysaccharide induced TNF-a expression in macrophages