◀ Back to YWHAE

PPP2R2B — YWHAE

Pathways - manually collected, often from reviews:

• NCI Pathway Database PDGFR-beta signaling pathway: PP2A complex (PPP2R1A-PPP2R2B-PPP2CA) → RAF1/14-3-3 (dimer) complex (RAF1-YWHAH_YWHAZ_YWHAQ_SFN_YWHAE_YWHAG_YWHAB) (modification, activates)
  Mason et al., EMBO J 1999, Ory et al., Curr Biol 2003, McKay et al., Proc Natl Acad Sci U S A 2009, Dhillon et al., Cell Signal 2009, Ritt et al., Mol Cell Biol 2010, Michaud et al., Mol Cell Biol 1995, Muslin et al., Cell 1996
  Evidence: assay, physical interaction
• NCI Pathway Database PDGFR-beta signaling pathway: PP2A complex (PPP2R1A-PPP2R2B-PPP2CA) → 14-3-3 family (YWHAH/YWHAZ/YWHAQ/SFN/YWHAE/YWHAG/YWHAB) (modification, activates)
  Mason et al., EMBO J 1999, Ory et al., Curr Biol 2003, McKay et al., Proc Natl Acad Sci U S A 2009, Dhillon et al., Cell Signal 2009, Ritt et al., Mol Cell Biol 2010, Michaud et al., Mol Cell Biol 1995, Muslin et al., Cell 1996
  Evidence: assay, physical interaction
• NCI Pathway Database PDGFR-beta signaling pathway: PP2A complex (PPP2R1A-PPP2R2B-PPP2CA) → 14-3-3 family (YWHAH/YWHAZ/YWHAQ/SFN/YWHAE/YWHAG/YWHAB) (modification, activates)
  Müller et al., Mol Cell 2001, Ory et al., Curr Biol 2003
  Evidence: mutant phenotype, assay
• NCI Pathway Database PDGFR-beta signaling pathway: PP2A complex (PPP2R1A-PPP2R2B-PPP2CA) → BRAF/14-3-3 complex (BRAF-YWHAH_YWHAZ_YWHAQ_SFN_YWHAE_YWHAG_YWHAB) (modification, activates)
  Ritt et al., Mol Cell Biol 2010
  Evidence: assay, physical interaction