Gene interactions and pathways from curated databases and text-mining

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CD4 — IFNB1

Text-mined interactions from Literome

Krakauer et al., Scand J Immunol 2006 (Multiple Sclerosis, Relapsing-Remitting) : Using flow cytometry, an enzyme linked immunosorbent assay and a real-time polymerase chain reaction, we studied in vivo IFN-beta induced effects on CD4 ( + ) T-lymphocyte chemokine receptor expression as these influence central nervous system ( CNS ) transmigration and inflammation
Chen et al., Eur J Immunol 2009 (Encephalomyelitis, Autoimmune, Experimental...) : Our further investigation demonstrated that IFN-beta also acted directly on the CD4 ( + ) T cells to regulate OPN and IL-17 expression through the type I IFN receptor mediated activation of STAT1 and suppression of STAT3 activity
Ramgolam et al., J Immunol 2009 (Multiple Sclerosis) : We have investigated the effect of IFN-beta-1a on dendritic cells (DCs) and naive CD4 ( + ) CD45RA ( + ) T cells derived from untreated MS patients and healthy controls in the context of Th17 cell differentiation