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CCR7 — EPHB2

Text-mined interactions from Literome

Adachi et al., Biochem Biophys Res Commun 2001 (Calcium Signaling...) : Induction of CCR7 expression in thymocytes requires both ERK signal and Ca ( 2+ ) signal
Li et al., Blood 2007 (MAP Kinase Signaling System) : Specific inhibition of ERK during CB DC maturation enhanced LPS induced up-regulation of CCR7 and CXCR4 on CB DCs and their chemotaxis toward CCL19 and CXCL12, to a level similar to that of mature AB DCs
Escribano et al., J Immunol 2009 : In keeping with its prosurvival role, stimulation of CCR7 induced phosphorylation/inhibition of GSK3beta, which was mediated by the prosurvival regulator Akt1, but it was independent of ERK1/2 , a key regulator of chemotaxis
Xu et al., PloS one 2011 (Carcinoma, Non-Small-Cell Lung...) : LY294002, a selective inhibitor of PI3K that prevents activation of the downstream Akt, did not weaken the effect of CCL21/CCR7 on P-ERK
Akuthota et al., Am J Respir Cell Mol Biol 2013 : Finally, primed eosinophils stimulated with CCL19 or CCL21 exhibited increased phosphorylation of ERK in response to both CCR7 ligands