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Fan et al., Mol Cell Biol 2000
:
Overexpression of Abi-1 inhibits epidermal growth factor (EGF) induced activation of extracellular signal regulated kinases ( Erks ) but does not affect EGF induced activation of c-Jun N-terminal kinase or Akt Aoki et al., Nat Genet 2003
(Chromosomal Instability...) :
Forced activation of mTOR through upstream regulator Akt also increased ABI in colon cancer cells