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MC1R — MSH2

Text-mined interactions from Literome

Maaser et al., Gut 2006 (Colitis...) : The anti-inflammatory functions of alpha MSH are mediated by the melanocortin1-receptor (MC1R) in an autoregulatory loop
Song et al., Pigment Cell Melanoma Res 2009 : The effect of alpha-MSH on 8-oxodG induction was mediated by activation of the melanocortin 1 receptor (MC1R) , as it was absent in melanocytes expressing loss-of-function MC1R, and blocked by concomitant treatment with an analog of agouti signaling protein (ASIP), ASIP-YY
Maresca et al., Pigment Cell Melanoma Res 2010 (Melanoma) : This work strengthens the correlation between melanogenesis and anti-oxidants, demonstrating the induction of catalase in response to a melanogenic stimulation, such as alpha-MSH dependent MC1R activation
Stanisz et al., Dermato-endocrinology 2011 : MC1R stimulation with a-MSH in wild type ( MC1R ( wt ) ) melanocytes results in an increase of intracellular cAMP and cellular proliferation
Suzuki et al., Endocrinology 1996 : To further analyze how melanotropins produce these biological effects, we investigated the regulation of the melanocortin receptor MC1R expression by alpha-MSH and ACTH using Northern blot analysis and determine the relative affinity of the receptor for the structurally similar peptides alpha-MSH, ACTH, beta-MSH, and gamma-MSH
Suzuki et al., J Invest Dermatol 1997 : Here we report that ASIP blocked the binding of alpha-melanocyte stimulating hormone ( alpha-MSH ) to the MC1R and inhibited the effects of alpha-MSH on human melanocytes