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CYP19A1 — SOD1

Text-mined interactions from Literome

Milczarek et al., J Steroid Biochem Mol Biol 2008 : EDTA, alpha-tocopherol, MgCl ( 2 ) and superoxide dismutase ( SOD ) prevent aromatase activity inhibition and cytochrome P450(AROM) degradation
LaPolt et al., Endocrinology 1995 : Although incubation with either forskolin or ( Bu ) 2cAMP alone stimulated estrogen production from granulosa cells, cotreatment with SOD significantly attenuated estrogen levels, indicating that SOD can inhibit aromatase activity at one or more post-FSH receptor sites ... The findings that SOD and activators of the cAMP dependent signaling pathway synergistically increase the levels of the second messenger cGMP and that ( Bu ) 2cGMP treatment attenuates FSH-, forskolin-, and cAMP induced aromatase activity suggest a potential mechanism of SOD action and demonstrate the antagonist action of cGMP on cAMP mediated estrogen production