Gene interactions and pathways from curated databases and text-mining

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CA1 — IL2

Text-mined interactions from Literome

Hybiske et al., Am J Physiol Lung Cell Mol Physiol 2007 (Calcium Signaling...) : In the absence of bacteria, there were no or only small differences among CF15, CF15-lacZ ( beta-galactosidase expressing ), CF15-wtCFTR ( wtCFTR corrected ), and CF15-DeltaF508CFTR ( to test ER retention of DeltaF508CFTR ) cells in NF-kappaB activity, interleukin (IL)-8 secretion, Ca(i) responses , and ER stress
Manger et al., J Clin Invest 1986 : Another T cell line, HUT 78, also produces IL-2 in response to a rise in [ Ca++]i and PMA ; however, in HUT 78, PMA alone induces low levels of IL-2 production that is not blocked by CsA