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CPOX — NOS3
Text-mined interactions from Literome
King et al., Neurosignals 2005
(Opioid-Related Disorders...) :
A non-inclusive list of examples of substances reported to block or reverse opioid antinociceptive tolerance include : substance P receptor ( NK-1 ) antagonists, calcitonin gene related peptide (CGRP) receptor antagonists,
nitric oxide ( NO ) synthase inhibitors, calcium channel blockers,
cyclooxygenase (COX) inhibitors , protein kinase C inhibitors, competitive and non-competitive antagonists of the NMDA ( N-methyl-D-aspartate ) receptor, AMPA ( alpha-amino-3-hydroxy-5-methyl-4 isoxazolepropionic acid ) antagonists, anti-dynorphin antiserum, and cholecystokinin (CCK) receptor antagonists
Stanley et al., Vascul Pharmacol 2009
(Diabetes Complications...) :
Uterine arteries from term-pregnant, diabetic and control C57Bl6/J mice were assessed using acetylcholine ( ACh ; 10 ( -10 ) -10 ( -5 ) M ) in the
presence or absence of a
nitric oxide ( NO ) synthase inhibitor ( L-NNA ; 10 ( -5 ) M ), a
cyclooxygenase (COX) inhibitor ( indomethacin ; 10 ( -5 ) M ) or the two in combination
Obermajer et al., Transplantation research 2012
:
We observed that PGE2 induces endogenous
cyclooxygenase (COX)2 expression in cultured monocytes, blocking their differentiation into CD1a+ dendritic cells (DCs) and
inducing the expression of indoleamine 2,3-dioxygenase 1, IL-4Ra,
nitric oxide synthase 2 and IL-10 - typical MDSC associated suppressive factors