We have a suspicion that you are an automated web bot software, not a real user. To keep our site fast for other users, we have slowed down this page. The slowdown will gradually disappear. If you think this is a mistake, please contact us at genome-www@soe.ucsc.edu. Also note that all data for hgGeneGraph can be obtained through our public MySQL server and all our software source code is available and can be installed locally onto your own computer. If you are unsure how to use these resources, do not hesitate to contact us.
UCSC Genome Browser Gene Interaction Graph
Gene interactions and pathways from curated databases and text-mining

◀ Back to PTGS2

ALOX15 — PTGS2

Text-mined interactions from Literome

Wu et al., Carcinogenesis 2003 (Stomach Neoplasms) : We found that : ( i ) SC-236 inhibited growth of gastric cancer cells mainly by inducing apoptosis ; ( ii ) SC-236 induced 15-LOX-1 expression and increased endogenous 13-S-HODE product, instead of 15-S-HETE during apoptosis ; ( iii ) SC-236 did not affect expression of COX-1, COX-2 , 5-LOX and 12-LOX ; and ( iv ) 15-LOX-1 inhibition suppressed SC-236 induced apoptosis
Xu et al., Neoplasia (New York, N.Y.) 2003 (Esophageal Neoplasms) : The COX-2 inhibitor, NS398, induced 15-LOX-2 expression in esophageal cancer cells, which is associated with reduced cell viability