Gene interactions and pathways from curated databases and text-mining

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EPHB2 — KL

Text-mined interactions from Literome

Kurosu et al., J Biol Chem 2006 : In addition, Klotho significantly enhanced the ability of FGF23 to induce phosphorylation of FGF receptor substrate and ERK in various types of cells
Shu et al., Cellular oncology (Dordrecht) 2013 (Carcinoma, Hepatocellular...) : Exogenous klotho gene expression also down-regulated the phosphorylation levels of the IGF-1 receptor, and the downstream Akt, ERK , and p70S6K proteins
Chen et al., J Neurosci 2013 : Phosphoprotein analysis indicated that Klotho 's downstream effects involve Akt and ERK signal pathways