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IGFBP3 — NR4A1

Text-mined interactions from Literome

Lee et al., J Biol Chem 2005 : This translocation is a type 1 IGF receptor signaling independent event as IGFBP-3 induces Nur77 translocation in R-cells ... GFP-Nur77 transfection into RXRalpha wild-type and knock-out mouse embryonic fibroblasts and subsequent treatment with IGFBP-3 show that RXRalpha is required for IGFBP-3 induced Nur77 translocation and apoptosis
Lee et al., Carcinogenesis 2007 (Prostatic Neoplasms) : We have recently described IGFBP-3 induced mitochondrial translocation of the nuclear receptors RXRalpha/Nur77 in the induction of prostate cancer ( CaP ) cell apoptosis