Gene interactions and pathways from curated databases and text-mining

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CCND1 — IRF6

Text-mined interactions from Literome

Vadiveloo et al., J Leukoc Biol 1999 : We have unexpectedly found that macrophages treated with lipopolysaccharide (LPS) express high levels of cyclin D2, even though LPS simultaneously represses cyclin D1 levels and potently blocks proliferation
Vadiveloo et al., Biochim Biophys Acta 2001 : Moreover, in both normal and NOSII-/- BMM, LPS inhibited the expression of cyclin D1 , a protein that is essential for proliferation in many cell types
Hobbs et al., Cell Immunol 1991 : We also analyzed constitutive and LPS induced IL-6 gene expression by the murine B cell lines : 70Z/3, 38C-13, WEHI-231, X16C, WEHI-279, and BCL1
Simpson et al., J Immunol 1985 (Leukemia, Experimental) : Phorbol esters, including PMA and phorbol dibutyrate ( PDBu ), were potent inhibitors of BCL-1 IgM secretion induced by either LPS or lymphokines ; half-maximal inhibition was obtained with 0.1 nM PMA and 0.8 nm PDBu
Roess et al., Cancer Res 1983 (Leukemia, Experimental) : Therefore, maximum TA effect in LPS stimulated BCL1 cells occurred when TA was added to cultures at the onset of mitogen stimulation
Lund et al., J Immunol 1993 (Lymphoma, B-Cell) : Furthermore, stimulation of BCL1 and CH12 cells with LPS resulted in a pronounced reduction in superantigen presentation, even though MMTV transcript levels were increased
Sulentic et al., Mol Pharmacol 1998 (Carcinoma, Hepatocellular...) : Conversely, TCDD induced inhibition of IgM secretion was not demonstrated in LPS stimulated BCL-1 cells, implicating a role for the AhR in the inhibition of B cell effector function ... LPS induced differentiation of the CH12.LX cells also resulted in a marked induction of Ahr expression which was not induced in LPS stimulated BCL-1 cells
Vadiveloo et al., J Biol Chem 1998 : Furthermore, LPS alone induced cyclin D2 but not cyclin D1