Reizner et al., J Mol Endocrinol 2005
(Breast Neoplasms) :
The WT1 Wilms ' tumor suppressor gene product interacts with estrogen receptor-alpha and regulates IGF-I receptor gene transcription in breast cancer cells ... The WT1 Wilms ' tumor suppressor gene product interacts with estrogen receptor-alpha and regulates IGF-I receptor gene transcription in breast cancer cells
Werner et al., Mol Cell Biol 1995
(Wilms Tumor) :
We have investigated the regulation of the insulin-like growth factor I receptor ( IGF-I-R ) gene promoter by the Wilms ' tumor suppressor WT1 in intact cells
Roberts et al., Endocr J 1996
(Wilms Tumor) :
During normal renal development, increased expression of the WT1 gene leads to repression of IGF-I receptor gene expression, allowing differentiation of the metanephrogenic blastema into renal epithelium