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KALRN — RAC1
Pathways - manually collected, often from reviews:
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Chakrabarti et al., Mol Cell Biol 2005
:
Furthermore, elevated
Kalirin expression resulted in catalytic activation of TrkA, as demonstrated by in vitro kinase assays and
increased NGF stimulated cellular activation of
Rac , Mek, and CREB
Koo et al., BMC cell biology 2007
:
Kalirin5 induced
Rac1 activation is increased by the expression of wild type Arf6 and decreased by Arf6T27N
Impey et al., Mol Cell Neurosci 2010
:
Additionally, we show that the miR132/p250GAP circuit
regulates Rac1 activity and spine formation by modulating synapse-specific
Kalirin7-Rac1 signaling