Gene interactions and pathways from curated databases and text-mining

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IL6 — MAP3K3

Text-mined interactions from Literome

Huang et al., Nat Immunol 2004 : MEKK3 forms a complex with TRAF6 in response to IL-1 and lipopolysaccharide (LPS) but not CpG, and is required for IL-1R- and TLR4 induced IL-6 production
Kim et al., Immunology 2007 : MEKK3 is essential for lipopolysaccharide induced interleukin-6 and granulocyte-macrophage colony stimulating factor production in macrophages