◀ Back to GRAP2
GRAP2 — TNFSF10
Text-mined interactions from Literome
Zhang et al., Cancer Biol Ther 2004
(Colonic Neoplasms) :
Our results suggest that activation of p38 MAP kinases does not play a major role in TRAIL mediated apoptosis in DLD1 cells and that lack of
TRAIL mediated
p38 MAP kinase activation may not be the mechanism of TRAIL-resistance in DLD1/TRAIL-R cells
Berg et al., FEBS J 2009
(Multiple Myeloma) :
Preceding cell death,
TRAIL activated nuclear factor kappaB, c-Jun N-terminal kinase,
p38 and p42/44 ... Although
TRAIL induced stimulation of c-Jun N-terminal kinase and
p38 was caspase dependent in a cell type-specific fashion, activation of nuclear factor kappaB and p42/44 was caspase independent in all cases
Fujikawa et al., Clin Exp Rheumatol 2009
:
TRAIL rapidly
induced apoptosis of FLS as well as the phosphorylation of extracellular signal regulated kinase ( ERK ),
p38 , c-Jun N-terminal kinase (JNK) and Akt
Kavuri et al., J Biol Chem 2011
:
Knockdown of cFLIP isoforms in primary human keratinocytes enhanced CD95L- and
TRAIL induced NF-?B
activation , and JNK and
p38 activation, underscoring the regulatory role of cFLIP for these DR-mediated signals