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MYD88 — NOS2
Pathways - manually collected, often from reviews:
Text-mined interactions from Literome
Means et al., J Immunol 2001
(Tuberculosis) :
Lastly, we demonstrated that a dominant negative
MyD88 mutant could
block Mtb induced activation of the TNF-alpha promoter, but not the
inducible NO synthase promoter, in murine macrophages
Torgler et al., J Immunol 2008
(Malaria) :
Sporozoite mediated hepatocyte wounding limits Plasmodium parasite development via
MyD88 mediated NF-kappa B activation and
inducible NO synthase expression
Rodriguez et al., J Leukoc Biol 2008
(Chlamydia Infections) :
Induction of
iNOS by Chlamydophila pneumoniae
requires MyD88 dependent activation of JNK ... Here, we demonstrate that induction of
iNOS in macrophages upon C. pneumoniae infection is
controlled by
MyD88 via two pathways : NF-kappaB activation and phosphorylation of the MAPK JNK, which leads to the nuclear translocation of c-Jun, one of the two components of the AP-1 complex
Ellman et al., Gene 2012
(Intervertebral Disc Degeneration) :
MyD88i also
attenuates the LPS- or IL-1 mediated induction of
iNOS and TLR-2 gene expression