◀ Back to HIF1A

HIF1A — PDLIM7

Text-mined interactions from Literome

Wakisaka et al., Mol Cell Biol 2004 (Epstein-Barr Virus Infections...) : Catalase, an H ( 2 ) O ( 2 ) scavenger, strongly suppresses LMP1 induced production of H ( 2 ) O ( 2 ), which results in a decrease in the expression of HIF-1 alpha induced by LMP1
Kondo et al., Cancer Res 2006 (Breast Neoplasms...) : Here, we explore the mechanism for HIF1alpha activation by LMP1 in nasopharyngeal epithelial cells : LMP1 up-regulates the level of Siah1 E3 ubiquitin ligase by enhancing its stability, which subsequently induces proteasomal degradation of prolyl HIF-hydroxylases 1 and 3 that normally mark HIF1alpha for degradation ... As a result, LMP1 prevents formation of von Hippel-Lindau/HIF1alpha complex, as shown by coimmunoprecipitation analyses