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APCS — TLR2

Text-mined interactions from Literome

Salio et al., Proc Natl Acad Sci U S A 2007 : We report that activation of human APCs by Toll-like receptor ligands ( TLR-L ) modulates the lipid biosynthetic pathway, resulting in enhanced recognition of CD1d associated lipids by iNKT cells, as defined by IFN-gamma secretion
Wack et al., Immunopharmacol Immunotoxicol 2008 : Bacterial capsular polysaccharides ( PS ) which naturally contain zwitterionic charge motifs ( ZPS ) possess specific immunostimulatory activity, leading to direct activation of antigen presenting cells (APCs) through Toll-like receptor 2 (TLR2) and of T cells in co-culture systems
Jones et al., J Immunol 2010 : These studies suggest that some age associated immune defects may be overcome by targeted activation of APCs by TLR ligands