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PDE3B — TNF

Text-mined interactions from Literome

Rahn Landström et al., Biochem J 2000 : We conclude that the lipolytic effect of TNF-alpha involves the down-regulation of PDE3B , which is associated with increased activation of PKA, presumably owing to increased levels of cAMP ... These results, which suggest that PDE3B is a novel target for long-term regulation by TNF-alpha and cAMP, could contribute to the understanding of the mechanisms of insulin resistance
Molnar-Kimber et al., Agents Actions 1993 : PDE-IV inhibitors and to a lesser extent, PDE-III inhibitors suppressed TNF alpha production
Matsumori et al., J Mol Cell Cardiol 1996 (Heart Failure) : All three PDE III inhibitors, amrinone, pimobendan and vesnarinone, inhibited TNF-alpha production, but vesnarinone 's inhibitory effect was the most prominent