◀ Back to ATM
ATM — MATK
Text-mined interactions from Literome
Zhou et al., J Biol Chem 2000
(Ataxia Telangiectasia) :
Prior treatment of cells with 2 mM caffeine inhibits such a change and markedly reduces radiation induced
ataxia-telangiectasia mutated (ATM) dependent
Chk2/Cds1 activation and phosphorylation
Flaggs et al., Curr Biol 1997
:
The association of Chk1 with meiotic chromosomes and levels of Chk1 protein depend upon a functional
Atm gene product, but
Chk1 is not
dependent upon p53 for meiosis I functions ... The
Atm dependent presence of
Chk1 in mouse cells and along meiotic chromosomes, and the late pachynema co-localization of Atr and Chk1 on the unsynapsed axes of the paired X and Y chromosomes, suggest that Chk1 acts as an integrator for Atm and Atr signals and may be involved in monitoring the processing of meiotic recombination