Gene interactions and pathways from curated databases and text-mining

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ATM — MATK

Text-mined interactions from Literome

Zhou et al., J Biol Chem 2000 (Ataxia Telangiectasia) : Prior treatment of cells with 2 mM caffeine inhibits such a change and markedly reduces radiation induced ataxia-telangiectasia mutated (ATM) dependent Chk2/Cds1 activation and phosphorylation
Flaggs et al., Curr Biol 1997 : The association of Chk1 with meiotic chromosomes and levels of Chk1 protein depend upon a functional Atm gene product, but Chk1 is not dependent upon p53 for meiosis I functions ... The Atm dependent presence of Chk1 in mouse cells and along meiotic chromosomes, and the late pachynema co-localization of Atr and Chk1 on the unsynapsed axes of the paired X and Y chromosomes, suggest that Chk1 acts as an integrator for Atm and Atr signals and may be involved in monitoring the processing of meiotic recombination