Chen et al., Blood 2006
(Lymphoma) :
BCR dependent activation of the SYK PTK initiates downstream signaling events and amplifies the original BCR signal
Rowley et al., J Biol Chem 1995
:
Syk protein-tyrosine kinase is regulated by tyrosine phosphorylated Ig alpha/Ig beta immunoreceptor tyrosine activation motif binding and autophosphorylation
Takata et al., FEBS Lett 1995
:
These results demonstrate that the BCR induced phosphorylation of Src-PTK is independent of Syk and that the kinase activity of Src-PTK is critical for BCR signaling
Kawauchi et al., Mol Immunol 1996
:
Ligation of the B cell Ag receptor (BCR) activates a protein-tyrosine kinase ( PTK ) and CD45 protein-tyrosine phosphatase ( PTPase ) -dependent signaling cascade that results in the activation of Ras
Luton et al., Mol Biol Cell 1998
:
Protein tyrosine kinase inhibitors or deletion of the last 30 amino acids of pIgR cytoplasmic tail prevents IgA stimulated protein tyrosine kinase activation, tyrosine phosphorylation of phospholipase C-gammal, production of inositol triphosphate, and the stimulation of transcytosis by dIgA