Gene interactions and pathways from curated databases and text-mining

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INS — PTH

Text-mined interactions from Literome

Anastasilakis et al., Horm Metab Res 2008 (Insulin Resistance) : Our data suggest that while subtle transient alterations of Ca and PTH within the normal range as in exogenous rhPTH 1-34 administration do not affect glucose homeostasis, the continuously elevated Ca and endogenous PTH levels as in pHPT affect insulin sensitivity and result in increased insulin secretion
Iida-Klein et al., Endocrinology 1991 (Osteosarcoma...) : Insulin acutely suppresses parathyroid hormone second messenger generation in UMR-106-01 osteoblast-like cells : differential effects on phospholipase C and adenylate cyclase activation ... Therefore, we examined the effects of insulin on PTH second messenger generation in UMR-106-01 rat osteoblastic osteosarcoma cells
Chang et al., Mol Cell Endocrinol 2009 : This research investigated the effects of PTH on insulin signaling in differentiated 3T3-L1 adipocytes
Hinton et al., Endocrinology 1991 : Effects of insulin on the synthesis, intracellular degradation, and secretion of parathormone ... The results suggested that the insulin mediated increase in PTH and SP-I secretion is largely due to its regulation of PTH and SP-I biosynthesis
Nikalji et al., Nephrol Dial Transplant 2011 (Hyperinsulinism...) : It is postulated that reversal of parathyroid hormone (PTH) mediated inhibition of insulin secretion, along with large doses of 1,25-dihydroxyvitamin D3 ( calcitriol ) were responsible for the increase in insulin secretion and consequent hypoglycemia in this patient
Di Rosa et al., Immunology 2011 (Bacterial Infections...) : Vitamin D3 inhibits parathyroid hormone secretion, adaptive immunity and cell proliferation, and at the same time promotes insulin secretion, innate immunity and stimulates cellular differentiation
Sugimoto et al., Kidney Int 1990 : Removal of insulin from the medium resulted in a suppression of PTH secretion similar to changes observed with high concentrations of glucose
Massry et al., Am J Med 1989 (Hyperlipidemias...) : Excess PTH suppresses insulin release from pancreatic islets, and the insulin deficiency results in carbohydrate intolerance
Iida-Klein et al., J Bone Miner Res 1989 : Moreover, insulin reduced PTH stimulation of the PKC activity ratio by 42 and 62 % at 30 s and 20 min, respectively ( p less than 0.02 )
Civitelli et al., Am J Physiol 1988 (Osteosarcoma) : Thus the hypothesis that PTH stimulated Ins-1,4,5P3 production initiates Ca2+ release and contributes to transient elevations of [ Ca2+ ] i is supported
BroulĂ­k et al., Endocrinol Exp 1987 (Hypoglycemia) : The effect of insulin induced hypoglycemic stress on parathyroid hormone serum level in man were evaluated
Akmal et al., J Clin Invest 1985 (Hyperglycemia...) : The data show that ( a ) glucose intolerance does not develop with CRF in the absence of PTH, ( b ) PTH does not affect metabolic clearance of insulin or tissue resistance to insulin in CRF, and ( c ) the normalization of metabolism in CRF in the absence of PTH is due to increased insulin secretion
Yamaguchi et al., Endocrinol Jpn 1979 : Effect of parathyroid hormone on the increase in serum glucose and insulin levels after a glucose load to thyroparathyroidectomized rats ... These results suggest that the effect of PTH on serum glucose does not involve insulin secretion
Gollaher et al., J Nutr 1984 : The present study was designed to test whether the calciuria associated with arginine stimulated insulin secretion is mediated by insulin inhibition of parathyroid hormone (PTH) activity
Armbrecht et al., FEBS Lett 1996 : However, insulin increased the capacity of parathyroid hormone (PTH) to elevate CYP24 mRNA levels by 3-4-fold and to increase 24-hydroxylase activity by 2-fold in the presence of 1,25 ( OH ) 2D
Matsushita et al., Nihon rinsho. Japanese journal of clinical medicine 1996 (Glucose Intolerance...) : Recent studies reported that high PTH levels impaired insulin secretion from pancreatic islets
Shimamoto et al., Tohoku J Exp Med 1995 (Hyperinsulinism) : The results suggested that, under the conditions of euglycemic hyperinsulinemia by glucose clamp technique, insulin increased the serum free Ca ion, and as a result, PTH was suppressed
Onyia et al., Bone 1997 : Neither insulin-like growth factor-1 (IGF-1) nor insulin stimulated proliferation PTH ( 1-34 ) and dexamethasone inhibited proliferation
Chen et al., Diabetes Res Clin Pract 1998 (Glucose Intolerance...) : Effects of parathyroid hormone infusion on glucose tolerance and glucose stimulated insulin secretion in normal and uremic rats