◀ Back to PTH
INS — PTH
Text-mined interactions from Literome
Anastasilakis et al., Horm Metab Res 2008
(Insulin Resistance) :
Our data suggest that while subtle transient alterations of Ca and PTH within the normal range as in exogenous rhPTH 1-34 administration do not affect glucose homeostasis, the continuously elevated Ca and endogenous
PTH levels as in pHPT affect insulin sensitivity and
result in increased
insulin secretion
Iida-Klein et al., Endocrinology 1991
(Osteosarcoma...) :
Insulin acutely
suppresses parathyroid hormone second messenger generation in UMR-106-01 osteoblast-like cells : differential effects on phospholipase C and adenylate cyclase activation ... Therefore, we examined the
effects of
insulin on
PTH second messenger generation in UMR-106-01 rat osteoblastic osteosarcoma cells
Chang et al., Mol Cell Endocrinol 2009
:
This research investigated the
effects of
PTH on
insulin signaling in differentiated 3T3-L1 adipocytes
Hinton et al., Endocrinology 1991
:
Effects of
insulin on the synthesis, intracellular degradation, and secretion of
parathormone ... The results suggested that the
insulin mediated
increase in
PTH and SP-I secretion is largely due to its regulation of PTH and SP-I biosynthesis
Nikalji et al., Nephrol Dial Transplant 2011
(Hyperinsulinism...) :
It is postulated that reversal of
parathyroid hormone (PTH) mediated inhibition of
insulin secretion, along with large doses of 1,25-dihydroxyvitamin D3 ( calcitriol ) were responsible for the increase in insulin secretion and consequent hypoglycemia in this patient
Di Rosa et al., Immunology 2011
(Bacterial Infections...) :
Vitamin D3 inhibits
parathyroid hormone secretion, adaptive immunity and cell proliferation, and at the same time
promotes insulin secretion, innate immunity and stimulates cellular differentiation
Sugimoto et al., Kidney Int 1990
:
Removal of
insulin from the medium
resulted in a suppression of
PTH secretion similar to changes observed with high concentrations of glucose
Massry et al., Am J Med 1989
(Hyperlipidemias...) :
Excess
PTH suppresses insulin release from pancreatic islets, and the
insulin deficiency
results in carbohydrate intolerance
Iida-Klein et al., J Bone Miner Res 1989
:
Moreover,
insulin reduced
PTH stimulation of the PKC activity ratio by 42 and 62 % at 30 s and 20 min, respectively ( p less than 0.02 )
Civitelli et al., Am J Physiol 1988
(Osteosarcoma) :
Thus the hypothesis that
PTH stimulated
Ins-1,4,5P3 production initiates Ca2+ release and contributes to transient elevations of [ Ca2+ ] i is supported
BroulĂk et al., Endocrinol Exp 1987
(Hypoglycemia) :
The
effect of
insulin induced hypoglycemic stress on
parathyroid hormone serum level in man were evaluated
Akmal et al., J Clin Invest 1985
(Hyperglycemia...) :
The data show that ( a ) glucose intolerance does not develop with CRF in the absence of PTH, ( b )
PTH does not affect metabolic clearance of insulin or tissue resistance to insulin in CRF, and ( c ) the normalization of metabolism in CRF in the absence of PTH is
due to increased
insulin secretion
Yamaguchi et al., Endocrinol Jpn 1979
:
Effect of
parathyroid hormone on the increase in serum glucose and
insulin levels after a glucose load to thyroparathyroidectomized rats ... These results suggest that the
effect of
PTH on serum glucose does not involve
insulin secretion
Gollaher et al., J Nutr 1984
:
The present study was designed to test whether the calciuria associated with arginine stimulated insulin secretion is mediated by
insulin inhibition of
parathyroid hormone (PTH) activity
Armbrecht et al., FEBS Lett 1996
:
However,
insulin increased the capacity of
parathyroid hormone (PTH) to elevate CYP24 mRNA levels by 3-4-fold and to increase 24-hydroxylase activity by 2-fold in the presence of 1,25 ( OH ) 2D
Matsushita et al., Nihon rinsho. Japanese journal of clinical medicine 1996
(Glucose Intolerance...) :
Recent studies reported that high
PTH levels
impaired insulin secretion from pancreatic islets
Shimamoto et al., Tohoku J Exp Med 1995
(Hyperinsulinism) :
The results suggested that, under the conditions of euglycemic hyperinsulinemia by glucose clamp technique,
insulin increased the serum free Ca ion, and as a result,
PTH was
suppressed
Onyia et al., Bone 1997
:
Neither
insulin-like growth factor-1 (IGF-1) nor insulin
stimulated proliferation
PTH ( 1-34 ) and dexamethasone inhibited proliferation
Chen et al., Diabetes Res Clin Pract 1998
(Glucose Intolerance...) :
Effects of
parathyroid hormone infusion on glucose tolerance and glucose
stimulated insulin secretion in normal and uremic rats