Gene interactions and pathways from curated databases and text-mining

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A2M — IL8

Text-mined interactions from Literome

Bauer et al., FEBS Lett 1985 : Murine interleukin 1 stimulates alpha 2-macroglobulin synthesis in rat hepatocyte primary cultures
Warburton et al., FEBS Lett 1993 : Interleukin-1 beta, interleukin-6 and transforming growth factor-beta synergize with hydrocortisone, increasing the synthesis of alpha 2-macroglobulin 2- to 4-fold, although they have no effect in the absence of hydrocortisone
Ramdin et al., Clin Exp Allergy 1998 : The purpose of this study was to investigate the effect of heparin, heparan sulphate and alpha2-macroglobulin on IL-8 binding to neutrophils and subsequent functional effects in vitro ... The binding of 125I-IL-8 to neutrophils in the presence of alpha2-macroglobulin appears to be, in part, through the specific IL-8 receptor