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PIK3R1 — STK3
Text-mined interactions from Literome
Arimura et al., J Biol Chem 2004
:
Both CD28 and its relative, inducible costimulator (ICOS), have a binding motif for phosphatidylinositol 3-kinase (PI3K) in their cytoplasmic tail, and the binding of
PI3K leads to activation of a
serine/threonine kinase , Akt
Bailey et al., Mol Endocrinol 2004
:
PI3K activates a downstream
serine/threonine kinase , Akt ; therefore, we investigated the role of Akt in the interaction between PRL and TGF-beta signaling
Jones et al., J Immunol 2005
:
Protein kinase B ( PKBalpha/Akt1 ) a
PI3K dependent
serine-threonine kinase , promotes T cell viability in response to many stimuli and regulates homeostasis and autoimmune disease in vivo
Omori et al., Immunity 2006
:
PI3K dependent activation of the
serine-threonine kinase , Akt, suppressed CSR, in part, through the inactivation of the Forkhead Box family ( Foxo ) of transcription factors