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IL8 — NPY6R
Text-mined interactions from Literome
Syeda et al., J Cell Physiol 2008
(MAP Kinase Signaling System) :
The HNP induced
IL-8 production was
blocked by the Src tyrosine kinase inhibitor
PP2 , MEK1/2 inhibitor U0126, and the phosphatidylinositol 3 kinase (PI3K) inhibitor LY294002, but not by the JNK inhibitor SP600125 in both cell types
Xu et al., Cell Adh Migr 2007
:
Interestingly, P-selectin did not
induce a detectable
interleukine-8 (IL-8) secretion ( < 0.1 ng/ml ) in 30 minutes, whereas a high concentration of IL-8 ( > 50 ng/ml ) was required to increase neutrophil adhesion to Fg. P-selectin induced neutrophil adhesion was significantly inhibited by
PP2 ( a Src kinase inhibitor ), but not by pertussis toxin ( PTX ; a GPCR inhibitor )