Gene interactions and pathways from curated databases and text-mining

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HNRNPD — XRN2

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

He et al., EMBO J 2006 : AUF1 proteins bind the ARE, undergo shuttling, and promote cytoplasmic ARE-mRNA decay through a poorly understood mechanism
Gratacós et al., Wiley Interdiscip Rev RNA 2010 : The role of AUF1 in regulated mRNA decay
Al-Khalaf et al., PloS one 2013 : p16(INK4A) Positively Regulates p21 ( WAF1 ) Expression by suppressing AUF1 dependent mRNA decay
DeMaria et al., J Biol Chem 1996 : These results support a role for AUF1 in ARE directed mRNA decay that is based upon its affinity for different AREs