Hermanns et al., J Biol Chem 2000
:
In the present study, we demonstrate that oncostatin M (OSM) , but not IL-6 or leukemia inhibitory factor, induces tyrosine phosphorylation of the Shc isoforms p52 and p66 and their association with Grb2 Chauhan et al., J Exp Med 1995
:
Oncostatin M induces association of Grb2 with Janus kinase JAK2 in multiple myeloma cells ... The results also demonstrate that OSM induces direct interaction of JAK2 kinase with Grb2 , an SH2/SH3 domain containing adaptor protein