Gene interactions and pathways from curated databases and text-mining

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NOS3 — WNK1

Text-mined interactions from Literome

Chen et al., J Biol Chem 2008 : Previous studies have shown that the acute stimulation of endothelial nitric-oxide synthase (eNOS) mRNA transcription by laminar shear stress is dependent on nuclear factor kappa B (NFkappaB) subunits p50 and p65 binding to a shear stress response element ( SSRE ) in the human eNOS promoter and that mutation of the SSRE abrogates the shear stimulated increase in eNOS promoter activity
Soares et al., J Immunol 1998 : We report here that adenovirus mediated expression of a dominant negative C-terminal truncation mutant of p65/RelA ( p65RHD ) inhibits the induction of proinflammatory genes, such as E-selectin, ICAM-1, VCAM-1, IL-8, and inducible nitric oxide synthase , in EC as efficiently as does I kappaB alpha