Pathways - manually collected, often from reviews:
OpenBEL Selventa BEL large corpus:
PDE4B
→
MAPK1
(directlyIncreases, PDE4B Activity)
Evidence: catalytic unit of pde4b,c and d families contains a single consensus site for phosphorylation by ERK, which in the PDE4D3 isoform is Ser579 ERK cannot phosphorylate PDE4A