Reynard et al., Mol Cell Biol 2000
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We show here that Cks1 is required for the protein kinase activity of budding yeast G ( 1 ) cyclin-CDK complexes ... The role of Cks1 in promoting G ( 1 ) cyclin-CDK protein kinase activity both in vitro and in vivo provides a simple molecular rationale for the essential role of CKS1 in progression through G ( 1 ) phase in budding yeast
Hattori et al., Genes Cells 2003
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Recent work has demonstrated the role of cdc kinase subunit 1 (Cks1) in the ubiquitin-proteasome dependent degradation of CDK inhibitor p27Kip1 protein as an essential cofactor for SCFSkp2 ubiquitin ligase