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MAPK8 — MDM2
Text-mined interactions from Literome
Paitel et al., J Biol Chem 2004
:
Neuronal PrPc likely controls p53 at a post-transcriptional level because the deletion of cellular prion protein is accompanied by a higher
Mdm2-like immunoreactivity and
reduced phosphorylated p38
MAPK expression
Jackson et al., J Biol Chem 2006
(MAP Kinase Signaling System) :
Inhibition of p38
MAPK or MEK via pharmacological means or expression of dominant negative proteins
inhibited the cytoplasmic accumulation of
Hdm2 and increased Hdm2 and p53 protein levels, whereas constitutively active p90Rsk promoted the nuclear export of Hdm2