Gene interactions and pathways from curated databases and text-mining

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FOS — ITGB1

Text-mined interactions from Literome

Eriksson et al., Exp Cell Res 2005 (MAP Kinase Signaling System) : AP-1 regulates alpha2beta1 integrin expression by ERK dependent signals during megakaryocytic differentiation of K562 cells ... Conversely, coexpression of JunD or c-Jun and c-Fos can induce alpha2beta1 integrin expression independently of upstream signals ... Taken together, the results show that AP-1 is a nuclear target of the ERK-pathway and mediates alpha2beta1 integrin expression during megakaryocytic differentiation of K562 cells
Cho et al., Ann N Y Acad Sci 2006 (Helicobacter Infections) : In conclusion, H. pylori activates Ras, NF-kappaB, and AP-1 and thus induces the expression of integrin alpha5 and integrin beta1 in gastric epithelial cells