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TSG101 — VPS28

Pathways - manually collected, often from reviews:

• KEGG Endocytosis: TSG101 → VPS28 (protein-protein, binding/association)
• Reactome Reaction: VPS28 → TSG101 (direct_complex) Stuchell et al., J Biol Chem 2004

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Bind Interaction: VPS28 — TSG101 Stuchell et al., J Biol Chem 2004
• IRef Bind Interaction: VPS28 — TSG101 Bishop et al., J Biol Chem 2001*
• IRef Bind Interaction: VPS28 — TSG101 von Schwedler et al., Cell 2003
• IRef Bind_translation Interaction: VPS28 — TSG101 (coimmunoprecipitation) Bishop et al., J Biol Chem 2001*
• IRef Bind_translation Interaction: VPS28 — TSG101 (unspecified method) Bishop et al., J Biol Chem 2001*
• IRef Bind_translation Interaction: VPS28 — TSG101 (two hybrid) Stuchell et al., J Biol Chem 2004
• IRef Bind_translation Interaction: VPS28 — TSG101 (two hybrid) von Schwedler et al., Cell 2003
• IRef Bind_translation Interaction: TSG101 — VPS28 (two hybrid) Martin-Serrano et al., Proc Natl Acad Sci U S A 2003
• IRef Biogrid Interaction: TSG101 — VPS28 (physical association, affinity chromatography technology) Stefani et al., Curr Biol 2011
• IRef Biogrid Interaction: TSG101 — VPS28 (physical association, affinity chromatography technology) Martin-Serrano et al., J Virol 2003
• IRef Biogrid Interaction: TSG101 — VPS28 (direct interaction, two hybrid) Stuchell et al., J Biol Chem 2004
• IRef Biogrid Interaction: TSG101 — VPS28 (direct interaction, two hybrid) von Schwedler et al., Cell 2003
• IRef Biogrid Interaction: TSG101 — VPS28 (direct interaction, pull down) Bishop et al., J Biol Chem 2001*
• IRef Biogrid Interaction: TSG101 — VPS28 (direct interaction, two hybrid) Venkatesan et al., Nat Methods 2009
• IRef Biogrid Interaction: TSG101 — VPS28 (direct interaction, two hybrid) Rual et al., Nature 2005
• MIPS CORUM ESCRT-I complex: ESCRT-I complex complex (TSG101-VPS28-VPS37C) Eastman et al., J Biol Chem 2005
• MIPS CORUM TSG101-VPS37B-VPS28 complex: TSG101-VPS37B-VPS28 complex complex (TSG101-VPS28-VPS37B) Stuchell et al., J Biol Chem 2004
• IRef Corum Interaction: Complex of VPS37B-VPS28-TSG101-TSG101-VPS37B-VPS28 (association, coimmunoprecipitation) Stuchell et al., J Biol Chem 2004
• IRef Corum Interaction: Complex of VPS37C-TSG101-VPS28 (association, anti tag coimmunoprecipitation) Eastman et al., J Biol Chem 2005
• IRef Hprd Interaction: Complex of VPS28-TSG101-HGS-TSG101-HGS-VPS28-TSG101-VPS28-HGS (in vivo) Bishop et al., J Cell Biol 2002
• IRef Hprd Interaction: VPS28 — TSG101 (in vivo) Bishop et al., J Biol Chem 2001*, Bishop et al., J Cell Biol 2002
• IRef Hprd Interaction: VPS28 — TSG101 (in vitro) Bishop et al., J Biol Chem 2001*, Bishop et al., J Cell Biol 2002
• IRef Intact Interaction: Complex of 17 proteins (physical association, tandem affinity purification) Hutchins et al., Science 2010
• IRef Intact Interaction: Complex of 21 proteins (association, anti tag coimmunoprecipitation) Morita et al., EMBO J 2007
• IRef Intact Interaction: Complex of TUBA1A-RPS18-MAP4K4-TSG101-VPS37B-VPS28-MVB12A-MVB12B-TUBA1C (association, tandem affinity purification) Pichlmair et al., Nature 2012
• IRef Intact Interaction: VPS28 — TSG101 (physical association, two hybrid pooling approach) Rual et al., Nature 2005
• IRef Intact Interaction: VPS28 — TSG101 (physical association, two hybrid array) Venkatesan et al., Nat Methods 2009
• IRef Intact Interaction: VPS28 — TSG101 (physical association, two hybrid pooling approach) Venkatesan et al., Nat Methods 2009
• IRef Intact Interaction: Complex of TSG101-VPS37B-CD2AP-VPS28 (association, anti tag coimmunoprecipitation) Morita et al., EMBO J 2007
• IRef Ophid Interaction: VPS28 — TSG101 (aggregation, interologs mapping) Brown et al., Bioinformatics 2005

Text-mined interactions from Literome

Pornillos et al., EMBO J 2002 : Human Tsg101 plays key roles in HIV budding and in cellular vacuolar protein sorting ( VPS )
Valiathan et al., Virology journal 2008 : In contrast, PMA induced downregulation of the HIV-1 receptor CD4 was independent of ESCRT-I and Vps4 ; HIV-1 Gag had no effect on this process
Morvan et al., Mol Biol Cell 2012 : Pkh1/2 dependent phosphorylation of Vps27 regulates ESCRT-I recruitment to endosomes