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IL6 — SYK

Text-mined interactions from Literome

Kitaura et al., J Immunol 2004 : By contrast, highly cytokinergic IgE induced receptor internalization is dependent on Lyn, but not other Src family kinases, Syk, or Btk, whereas degranulation, IL-6 production, and survival require Syk
Ulanova et al., Am J Physiol Lung Cell Mol Physiol 2005 : Syk mediated signaling regulates IL-6 and ICAM-1 expression and may be important in the pathophysiology of lung inflammation
Skrzypek et al., Microbes Infect 2009 : Indeed, specific Syk inhibition significantly suppressed the production of IL-12, IL-6 , and TNF-alpha
Fang et al., Glycoconj J 2012 (Sarcoma) : It induced TNF-a and IL-6 production and the activation of Syk and NF-?B signaling in resident peritoneal macrophages from ICR mice, which could be significantly inhibited by the blocking reagent laminarin
Rao et al., J Biol Chem 2013 (Calcium Signaling) : In contrast to its effect on TNFa, Syk deficiency did not affect IL-6 secretion, suggesting that Syk dependent signals participate in differential sorting of cytokines, thus tailoring the cytokine response