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A2M — APC

Text-mined interactions from Literome

Chan et al., Thromb Haemost 2004 : APC , APC-PCI and APC-alpha1AT were also reduced and total APC-alpha2M increased in newborn plasma on HUVEC
Heeb et al., J Biol Chem 1991 : Purified alpha 2M and alpha 2AP inhibited APC in the presence of Ca2+ ( k2 = 99 and 100 M-1 S-1, respectively
Hoogendoorn et al., Blood 1991 : These data show that alpha 2M binds and inhibits APC in vitro and the interaction is both metal-ion and active-site dependent, requiring functionally intact alpha 2M