Gene interactions and pathways from curated databases and text-mining

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APC — IL2RA

Text-mined interactions from Literome

Manirarora et al., PloS one 2008 (Diabetes Mellitus) : APC activation restores functional CD4 ( + ) CD25 ( + ) regulatory T cells in NOD mice that can prevent diabetes development
Toyooka et al., Int Immunol 1996 : Moreover, IL-2R expression and proliferation induced by stimulation with bm12 APC was inhibited by CTLA-4-Ig, a soluble recombinant fusion protein capable of blocking the CD28 co-stimulatory signals not only stimulate IL-2 production but also induce IL-2R expression by an IL-2 independent mechanism