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IRF6 — TRAM2

Text-mined interactions from Literome

Fitzgerald et al., J Exp Med 2003 : LPS-TLR4 signaling to IRF-3/7 and NF-kappaB involves the toll adapters TRAM and TRIF
Sacre et al., J Immunol 2007 : To investigate a potential role for TRAM in LPS signaling in human M-CSF derived macrophages, we engineered an adenoviral construct expressing dominant negative TRAM-C117H ( AdTRAMdn )
Georgel et al., Virology 2007 : Downstream of TRAM , IRF7 activation leads to a type I IFN response
Zhao et al., Am J Chin Med 2008 : The results indicate that LPS increased the expression of TLR4, MyD88, TRAF-6, TRAM and TRIF, but had no influence on TLR3, while poly ( I:C ) up-regulated the expression of TLR3, MyD88, TRAM and TRIF ... 3-phenyl-propenal significantly decreased the expression of LPS induced TLR4, MyD88, TRAF-6, while possessing no effect on LPS induced TRAM and TRIF expression in Raw264.7 cells