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CST7 — CTSB

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Hprd Interaction: CTSB — CST7 (in vitro) Halfon et al., J Biol Chem 1998*, Ni et al., J Biol Chem 1998*
• IRef Ophid Interaction: CTSB — CST7 (aggregation, interologs mapping) Brown et al., Bioinformatics 2005

Text-mined interactions from Literome

Saleh et al., J Exp Ther Oncol 2003 (Stomach Neoplasms) : Regulation of cathepsin B and L expression in vitro in gastric cancer tissues by egg cystatin
Cegnar et al., J Nanosci Nanotechnol 2006 (Neoplasms) : On the contrary, free cystatin in solution did not internalise into the cells and inhibit cathepsin B
Kocevar et al., Chem Biol Drug Des 2007 : We demonstrated that palmitoylated cystatin rapidly internalized into the cell and caused a complete loss of cathepsin B activity
Kocevar et al., Chem Biol Drug Des 2008 : The experiments showed that acylated cystatin quickly internalized into the cells and effectively inhibited cathepsin B
Gerhartz et al., FEBS Lett 1997 : Surprisingly, however, cathepsin B was inhibited 15-fold more strongly by quail cystatin ( Ki = 47 pM ; k ( on ) = 19x10 ( 7 ) M ( -1 ) s ( -1 ) ; k ( off ) = 9x10 ( -4 ) s ( -1 ) ) than by chicken cystatin ( Ki = 784 pM ; k ( on ) = 2.9x10 ( 7 ) M ( -1 ) s ( -1 ) ; k ( off ) = 24x10 ( -4 ) s ( -1 ) )