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LOX — SETD2

Text-mined interactions from Literome

Pez et al., Cancer Res 2011 (Colorectal Neoplasms) : Thus, we hypothesized that LOX might regulate expression of HIF-1 to create a self timing regulatory circuit ... Using human colorectal carcinoma cell lines in which HIF-1 and LOX expression could be modulated, we showed that LOX induction enhanced HIF-1 expression, whereas LOX silencing reduced it
Goto et al., Cell Struct Funct 2013 (Breast Neoplasms...) : Lysyl oxidase (LOX) , a matrix remodeling factor, is induced by HIF-1a under hypoxic conditions and associated with tumor growth and metastasis
Dubey et al., J Am Chem Soc 2013 (Breast Neoplasms...) : It effectively inhibits HIF1 induced activation of VEGFA, LOX , Glut1, and c-Met genes in a panel of cell lines representing breast and lung cancers