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RHO — SPP1

Text-mined interactions from Literome

Lee et al., Cell 1999 : SPP induces the Gi/mitogen activated protein kinase/cell survival pathway and the small GTPase Rho- and Raccoupled adherens junction assembly
Paik et al., J Biol Chem 2001 : Indeed, SPP induced Rho activation in an adherence independent manner, whereas Rac activation was dispensible for cell attachment and focal contact formation
Porcelli et al., Cell Signal 2002 : SPP induced PLD activation and cytoskeletal remodelling were insensitive to brefeldin A and toxin B from Clostridium difficile, which conversely blocked the effect of LPA, suggesting that the monomeric GTPases ADP ribosylation factor ( ARF ) and Rho are involved in LPA, but not in SPP responses
Wongkhantee et al., J Periodontol 2007 (Alveolar Bone Loss) : In addition, the upregulation of OPN was diminished by Rho kinase inhibitor but not by cytochalasin B